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KMID : 0359920140330030161
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Korean Journal of Nephrology
2014 Volume.33 No. 3 p.161 ~ p.164
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Nephrotic syndrome complicated with portal, splenic, and superior Nephrotic syndrome complicated with portal, splenic, and superior
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Park Bong-Soo
Park Si-Hyung
Jin Kyu-Bok
Choi Gi-Bok
Park Kang-Min
Jo Kyeong-Min
Kim Yang-Wook
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Abstract
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Thromboembolism is a major complication of nephrotic syndrome. Renal vein thrombosis and deep vein thrombosis are relatively common, especially in membranous nephropathy. However, the incidence of portal vein and superior mesenteric vein (SMV) thrombosis in patients with nephrotic syndrome is very rare. To date, several cases of portal vein thrombosis treated by anticoagulation therapy, not by thrombolytic therapy, have been reported as a complication of nephrotic syndrome. Here, we report a case of portal, splenic, and SMV thrombosis in a patient with a relapsed steroid dependent minimal change disease who was treated successfully with anticoagulation and thrombolytic therapy using urokinase. Radiologic ?ndings and his clinical conditions gradually improved. Six months later, a complete remission of the nephrotic syndrome was observed and the follow-up computed tomography scan showed the disappearance of all portal vein, splenic vein, and SMV thrombi.
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KEYWORD
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Complications, Nephrotic syndrome, Thrombolytic therapy, Venous thrombosis
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